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In response to the recommended vaccines in older-aged individuals, sex differences occur in response to those that protect against influenza, tetanus, pertussis, shingles, and pneumococcal infections. The efficacy of vaccines recommended for older-aged adults is consistently greater for females than for males. Gender differences as well as biological sex differences can influence vaccine uptake, responses, and outcome in older-aged individuals, which should influence guidelines, formulations, and dosage recommendations for vaccines in the elderly. Based on data analyses from the U. Census Bureau, the projections for are that the population of people over the age of 65 will almost double the estimated population of
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Sex and Gender Impact Immune Responses to Vaccines Among the Elderly

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